CVS Practice Test 2025 – Complete Exam Preparation

When ischemic changes are noted in leads II, III, and aVF on an electrocardiogram (ECG), it indicates that the inferior part of the heart may be affected. These specific leads monitor the inferior wall of the left ventricle, which is primarily supplied by the right coronary artery in the majority of individuals, especially those who are right-dominant in their coronary circulation.

The right coronary artery typically supplies the right atrium, most of the right ventricle, parts of the left ventricle (the inferior wall), and the sinoatrial (SA) and atrioventricular (AV) nodes. When ischemia occurs in leads II, III, and aVF, it suggests reduced blood flow or obstruction in the areas supplied by this artery, highlighting its essential role in the vascularization of the heart's inferior wall.

In contrast, the left circumflex artery mainly supplies the lateral wall of the left ventricle, while the left anterior descending artery is predominantly associated with the anterior aspect of the heart, affecting leads V1 through V4. The anterior descending artery is often a term that refers specifically to the left anterior descending artery itself, which reinforces that the specific inferior ischemia marked by the